Leukoderma is a loss of skin pigment, especially
in patches, caused by a number of disorders and contact with various
chemicals. Loss of skin pigment causes white spots or patches.
It may occur following the resolution of areas of eczema and of
psoriasis. Residual hypopigmentation on the skin of the neck in patients
with secondary syphilis is termed leukoderma colli. Occupational
leukoderma occurs in workers in contact with the monobenzyl ether of
hydroquinone, phenolic germicidal preparations, and butylcatechol.